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1901
2009
Prize category:

The Nobel Prize in Physiology or Medicine 1998

Robert F. Furchgott, Louis J. Ignarro, Ferid Murad

The Nobel Prize in Physiology or Medicine 1998

Nobel Prize Award Ceremony

Robert F. Furchgott

Robert F. Furchgott

Louis J. Ignarro

Louis J. Ignarro

Ferid Murad

Ferid Murad

NO has many Clinical Applications

Today it is known that NO is also an important signalling molecule outside the cardiovascular system and has become a useful tool in the practice of medicine:
 Neurons in the brain NO can enhance the olfactory sense No is released in increased quantities in inflammation, a fact that can be used for diagnostic purposes
 

NO is important for signalling between nerve cells in the brain


Macrophage

NO is involved in the normal defence against bacterial and parasitic infections

NO initiates erection of the penis by dilating blood vessels
NO can be inhaled to specifically treat high blood pressure in the lungs of newborns
  Photo by Tommie Lindberg

Alfred Nobel suffered from angina pectoris and was prescribed nitroglycerine. In a letter to a friend he wrote:
  "It sounds like the irony of fate that I have been prescribed nitroglycerine internally. They have named it Trinitrin in order not to upset pharmacists and the public.

Your affectionate friend,

A. Nobel"


TO CITE THIS PAGE:
MLA style: "The Nobel Prize in Physiology or Medicine 1998". Nobelprize.org. 3 Sep 2010 http://nobelprize.org/nobel_prizes/medicine/laureates/1998/illpres/application.html