The Nobel Prize laureates are required “to give a lecture on a subject connected with the work for which the prize has been awarded according to the Nobel Foundation statutes. The lecture should be given before, or no later than six months after, the Nobel Prize award ceremony, which takes place in Stockholm or, in the case of the peace prize, in Oslo on 10 December.

Videos of Nobel Prize lectures in physiology or medicine

2023

Developing mRNA for therapy
Nobel Prize lecture by Katalin Karikó

Nucleoside Modified mRNA-LNP Therapeutics
Nobel Prize lecture by Drew Weissman

2022

The Neandertal Genome and the Evolution of Modern Humans
Nobel Prize lecture by Svante Pääbo

2021

From peppers to peppermints: insights into thermosensation and pain
Nobel Prize lecture by David Julius

How do you feel? The molecules that sense touch
Nobel Prize lecture by Ardem Patapoutian

2020

Nobel Prize lecture by Harvey J. Alter

Nobel Prize lecture by Michael Houghton

Nobel Prize lecture by Charles M. Rice

2019

The von Hippel-Lindau Tumor Suppressor Protein: Insights into Oxygen Sensing
Nobel Prize lecture by William G. Kaelin Jr

Elucidation of Oxygen Sensing Systems in Human and Animal Cells
Nobel Prize lecture by Sir Peter J. Ratcliffe

Hypoxia-Inducible Factors in Physiology and Medicine
Nobel Prize lecture by Gregg L. Semenza

2018

Immune Checkpoint Blockade in Cancer Therapy: New insights, opportunities, and prospects for cures
Nobel Prize lecture by James P. Allison

Serendipities of acquired immunity
Nobel Prize lecture by Tasuku Honjo

2017

The Little Flies: Multifaceted Basic Research Coming Out Better than Intended
Nobel Prize lecture by Jeffrey C. Hall

The Circadian Clock, Transcriptional Feedback and the Regulation of Gene Expression
Nobel Prize lecture by Michael Rosbash

Time Travels: A 40 Year Journey from Drosophila’s Clock Mutants to Human Circadian Disorders
Nobel Prize lecture by Michael W. Young

2016

Autophagy – an Intracellular Recycling System
Nobel Prize lecture by Yoshinori Ohsumi

2015

Ivermectin: A Reflection on Simplicity
Nobel Prize lecture by William C. Campbell

A Splendid Gift from the Earth: The Origins & Impact of Avermectin
Nobel Prize lecture by Satoshi Ōmura

Discovery of Artemisinin – A Gift from Traditional Chinese Medicine to the World
Nobel Prize lecture by Youyou Tu

2014

Spatial Cells in the Hippocampal Formation
Nobel Prize lecture by John O’Keefe

Grid Cells, Place Cells and Memory
Nobel Prize lecture by May-Britt Moser

Grid Cells and the Enthorinal Map of Space
Nobel Prize lecture by Edvard I. Moser

2013

The Principle of Membrane Fusion in the Cell
Nobel Prize lecture by James E. Rothman

Genetic and Biochemical Dissection of the Secretory Pathway
Nobel Prize lecture by Randy W. Schekman

A Molecular Machine for Neurotransmitter Release
Nobel Prize lecture by Thomas C. Südhof

2012

The Egg and the Nucleus: A Battle for Supremacy
Nobel Prize lecture by Sir John B. Gurdon

A Winding Road to Pluripotency
Nobel Prize lecture by Shinya Yamanaka

2011

How Mammals Sense Infection: From Endotoxin to the Toll-like Receptors
Nobel Prize lecture by Bruce A. Beutler

Evolutionary Perspectives of Innate Immunity: Studies with Drosophila
Nobel Prize lecture by Jules A. Hoffmann

Ralph Steinman and the Discovery of Dendritic Cells
Nobel Prize lecture for Ralph M. Steinman

2010

Nobel Prize Symposium in Honour of Robert G. Edwards: Bob Edwards and IVF: The Early Days
Nobel Symposium

2009

Telomeres and Telomerase: The Means to the End
Nobel Prize lecture by Elizabeth H. Blackburn

Telomerase Discovery: The Excitement of Putting Together Pieces of the Puzzle
Nobel Prize lecture by Carol W. Greider

DNA Ends: Just the Beginning
Nobel Prize lecture by Jack W. Szostak

2008

The Search for Infectious Causes of Human Cancers: Where and Why?
Nobel Prize lecture by Harald zur Hausen

HIV: a Discovery Opening the Road to Novel Scientific Achievements and Global Health Improvement
Nobel Prize lecture by Françoise Barré-Sinoussi

25 Years of Research on AIDS – Lessons and Prospects for Cure and Vaccine
Nobel Prize lecture by Luc Montagnier

2007

Gene Targeting in the 21st Century: Mouse Models of Human Disease from Cancer to Psychiatric Disorders
Nobel Prize lecture by Mario R. Capecchi

ES Cells: The Mouse Source – Vehicle for Mammalian Experimental Genetics
Nobel Prize lecture by Sir Martin J. Evans

Turning Pages
Nobel Prize lecture by Oliver Smithies

2006

Gene Silencing by Double Stranded RNA
Nobel Prize lecture by Andrew Z. Fire

Return to the RNAi World: Rethinking Gene Expression and Evolution
Nobel Prize lecture by Craig C. Mello

2005

Helicobacter Connections
Nobel Prize lecture by Barry J. Marshall

Helicobacter – The Ease and Difficulty of a New Discovery
Nobel Prize lecture by J. Robin Warren

2004

Scents and Sensibility: A Molecular Logic of Olfactory Perception
Nobel Prize lecture by Richard Axel

Unraveling the Sense of Smell
Nobel Prize lecture by Linda B. Buck

2003

All Science is Interdisciplinary – from Magnetic Moments to Molecules to Men
Nobel Prize lecture by Paul C. Lauterbur

Snap-Shot MRI
Nobel Prize lecture by Sir Peter Mansfield

2002

Nature’s Gift to Science
Nobel Prize lecture by Sydney Brenner

Worms, Life and Death
Nobel Prize lecture by H. Robert Horvitz

C. elegans: The Cell Lineage and Beyond
Nobel Prize lecture by John E. Sulston

2001

Yeast and Cancer
Nobel Prize lecture by Leland H. Hartwell

Protein Synthesis, Proteolysis, and Cell Cycle Transitions
Nobel Prize lecture by Tim Hunt

Controlling the Cell Cycle
Nobel Prize lecture by Sir Paul Nurse

2000

A Half-Century of Neurotransmitter Research: Impact on Neurology and Psychiatry
Nobel Prize lecture by Arvid Carlsson

The Neurobiology of Dopamine Signaling
Nobel Prize lecture by Paul Greengard

The Molecular Biology of Memory Storage: A Dialog between Genes and Synapses
Nobel Prize lecture by Eric R. Kandel

1999

Protein Targeting
Nobel Prize lecture by Günter Blobel

1998

Endothelium-Derived Relaxing Factor: Discovery, Early Studies, and Identification as Nitric Oxide
Nobel Prize lecture by Robert F. Furchgott

Nitric Oxide: A Unique Endogenous Signaling Molecule in Vascular Biology
Nobel Prize lecture by Louis J. Ignarro

Discovery of Some of the Biological Effects of Nitric Oxide and Its Role in Cell Signaling
Nobel Prize lecture by Ferid Murad

1997

Prions
Nobel Prize lecture by Stanley B. Prusiner

1996

Cell Mediated Immunity in Virus Infections
Nobel Prize lecture by Peter C. Doherty

Cellular Immune Recognition and the Biological Role of Major Transplantation Antigens
Nobel Prize lecture by Rolf M. Zinkernagel

1995

The Bithorax Complex: The First Fifty Years
Nobel Prize lecture by Edward B. Lewis

The Identification of Genes Controlling Development in Flies and Fishes
Nobel Prize lecture by Christiane Nüsslein-Volhard

From Molecular Patterns to Morphogenesis: The Lessons from Drosophila
Nobel Prize lecture by Eric F. Wieschaus

1994

G Proteins and Regulation of Adenylyl Cyclase
Nobel Prize lecture by Alfred G. Gilman

Signal Transduction: Evolution of an Idea
Nobel Prize lecture by Martin Rodbell

1993

An Amazing Distortion in DNA Induced by a Methyltransferase
Nobel Prize lecture by Richard J. Roberts

Split Genes and RNA Splicing
Nobel Prize lecture by Phillip A. Sharp

1992

Protein Phosphorylation and Cellular Regulation, II
Nobel Prize lecture by Edmond H. Fischer

Protein Phosphorylation and Cellular Regulation, I
Nobel Prize lecture by Edwin G. Krebs

1991

Ion Channels for Communication Between and Within Cells
Nobel Prize lecture by Erwin Neher

Elementary Steps in Synaptic Transmission Revealed by Currents through Single Ion Channels
Nobel Prize lecture by Bert Sakmann

1990

The First Successful Organ Transplants in Man
Nobel Prize lecture by Joseph E. Murray

Bone Marrow Transplantation – Past, Present and Future
Nobel Prize lecture by E. Donnall Thomas

1989

Retroviruses and Oncogenes II
Nobel Prize lecture by J. Michael Bishop

Retroviruses and Oncogenes I
Nobel Prize lecture by Harold E. Varmus

1988

Drugs from Emasculated Hormones: The Principles of Syntopic Antagonism
Nobel Prize lecture by Sir James W. Black

The Purine Path to Chemotherapy
Nobel Prize lecture by Gertrude B. Elion

Selective Inhibitors of Dihydrofolate Reductase
Nobel Prize lecture by George H. Hitchings

1987

Somatic Generation of Immune Diversity
Nobel Prize lecture by Susumu Tonegawa

1986

Epidermal Growth Factor
Nobel Prize lecture by Stanley Cohen

The Nerve Growth Factor: Thirty-Five Years Later
Nobel Prize lecture by Rita Levi-Montalcini

1985

A Receptor-Mediated Pathway for Cholesterol Homeostasis
Nobel Prize lecture by Michael S. Brown

A Receptor-Mediated Pathway for Cholesterol Homeostasis
Nobel Prize lecture by Joseph L. Goldstein

1984

The Generative Grammar of the Immune System
Nobel Prize lecture by Niels K. Jerne

Derivation and Diversification of Monoclonal Antibodies
Nobel Prize lecture by Georges J.F. Köhler

From the Structure of Antibodies to the Diversification of the Immune Response
Nobel Prize lecture by César Milstein

1983

The Significance of Responses of the Genome to Challenge
Nobel Prize lecture by Barbara McClintock

1982

The Prostaglandins: From the Laboratory to the Clinic
Nobel Prize lecture by Sune K. Bergström

From Studies of Biochemical Mechanisms to Novel Biological Mediators: Prostaglandin Endoperoxides, Thromboxanes and Leukotrienes
Nobel Prize lecture by Bengt I. Samuelsson

Adventures and Excursions in Bioassay: The Stepping Stones to Prostacyclin
Nobel Prize lecture by John R. Vane

1981

Some Effects of Disconnecting the Cerebral Hemispheres
Nobel Prize lecture by Roger W. Sperry

Evolution of Ideas on the Primary Visual Cortex, 1955-1978: A Biased Historical Account
Nobel Prize lecture by David H. Hubel

The Postnatal Development of the Visual Cortex and the Influence of Environment
Nobel Prize lecture by Torsten N. Wiesel

1980

The Role of MHC Gene Products in Immune Regulation and Its Relevance to Alloreactivity
Nobel Prize lecture by Baruj Benacerraf

The Major Histocompatibility Complex in Man – Past, Present, and Future Concepts
Nobel Prize lecture by Jean Dausset

Studies in Histocompatibility
Nobel Prize lecture by George D. Snell

1979

Early Two-Dimensional Reconstruction and Recent Topics Stemming from It
Nobel Prize lecture by Allan M. Cormack

Computed Medical Imaging
Nobel Prize lecture by Godfrey N. Hounsfield

1973

Decoding the Language of the Bee
Nobel Prize lecture by Karl von Frisch

Analogy as a Source of Knowledge
Nobel Prize lecture by Konrad Lorenz

Ethology and Stress Diseases
Nobel Prize lecture by Nikolaas Tinbergen

Links to more lectures with Nobel Prize laureates:
Lectures with Nobel Prize laureates in physics
Lectures with Nobel Prize laureates in chemistry
Lectures with Nobel Prize laureates in physiology or medicine
Lectures with Nobel Prize laureates in literature
Lectures with Nobel Peace Prize laureates
Lectures with laureates in economic sciences