Otto Loewi
Facts
Photo from the Nobel Foundation archive.
Otto Loewi
The Nobel Prize in Physiology or Medicine 1936
Born: 3 June 1873, Frankfurt-on-the-Main, Germany
Died: 25 December 1961, New York, NY, USA
Affiliation at the time of the award: Graz University, Graz, Austria
Prize motivation: “for their discoveries relating to chemical transmission of nerve impulses”
Prize share: 1/2
Work
At the beginning of the 20th century, it was known that the nervous system’s signals are conveyed with the help of electrical impulses. However, it was unclear whether the signals were also conveyed by chemical substances. In 1921 Otto Loewi stimulated the heart of a frog with electrical impulses and had it pump a small amount of nutrient solution. When the fluid was transferred to another heart, it operated in a similar way. This provided proof that chemical substances convey nerve signals to organs. Loewi verified the role of other substances, including acetylcholine, in this context.
Nobel Prizes and laureates
Six prizes were awarded for achievements that have conferred the greatest benefit to humankind. The 12 laureates' work and discoveries range from proteins' structures and machine learning to fighting for a world free of nuclear weapons.
See them all presented here.
