Earl W. Sutherland, Jr.
Facts
Earl W. Sutherland, Jr.
The Nobel Prize in Physiology or Medicine 1971
Born: 19 November 1915, Burlingame, KS, USA
Died: 9 March 1974, Miami, FL, USA
Affiliation at the time of the award: Vanderbilt University, Nashville, TN, USA
Prize motivation: “for his discoveries concerning the mechanisms of the action of hormones”
Prize share: 1/1
Work
Signals between different parts of the body are conveyed by small electrical impulses and by chemical substances, hormones and signal substances. Communication also takes place between different cell parts. Earl Sutherland investigated how hormones, especially adrenaline, work. He showed how signals from one cell to another are conveyed by a messenger—the hormone—and how signals within the cell are then conveyed by another messenger. Around 1960 he showed how cyclic adenosine monophosphate (cAMP) serves as the secondary messenger within the cell.
Nobel Prizes and laureates
Six prizes were awarded for achievements that have conferred the greatest benefit to humankind. The 12 laureates' work and discoveries range from proteins' structures and machine learning to fighting for a world free of nuclear weapons.
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