Interview transcript Dr Ciechanover, Dr Hershko and Dr Rose, my congratulations to the Nobel Prize and welcome to this interview. I know that you two started as medical doctors but you are in science now, and you get the prize for scientific research. How come you left medicine? Avram Hershko: Well, I…

Links to other sites Video Professor Aaron Ciechanover: ‘Intracellular Proteolysis as a Future Drug Development Platform’ from Technion

Transcript from an interview with the 2004 Nobel Laureates in Chemistry Aaron Ciechanover, Avram Hershko and Irwin Rose, on 9 December 2004. Interviewer is Joanna Rose, science writer. Dr Ciechanover, Dr Hershko and Dr Rose, my congratulations to the Nobel Prize…

I was born on December 31, 1937, in Karcag, Hungary. Karcag is a small town of around 25,000 inhabitants, about 150 kilometers east of Budapest. It had a Jewish community of nearly one thousand people. My father, Moshe Hershko, was a schoolteacher in the Jewish elementary school in Karcag; most of the Jewish children in…

  The Nobel Prize in Chemistry 2004         Further Reading     Scientific American nr 1/2001 The Ubiquitin System  Ciechanover et al. Proc. Natl. Acad. Sci. USA, 77, 1365-1368, 1980 Hershko et al. Proc. Natl. Acad. Sci. USA, 77, 1783-1786, 1980     Contents: |  |  |  |  |  |  |  | …

English The Nobel Prize in Chemistry 2004 A human cell contains some hundred thousand different proteins. These have numerous important functions: as accelerators of chemical reactions in the form of enzymes, as signal substances in the form of hormones, as important actors in the immune defence and by being responsible for the cell’s form and…

We left my birthplace, Brooklyn, New York in 1939 when I was 13. I enjoyed the ethnic variety and the interesting students in my public school, P.S. 134. The kids in my neighborhood were only competitive in games although unfriendly gangs tended to define the limits of our neighborhood. The major extracurricular activities that I…

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The most deeply formative events of my scientific career long preceded my first contact with the research community; indeed, some of them preceded my birth. My grandparents emigrated from Europe in the aftermath of World War I, as young teenagers; on my father’s side they came from Poland and on my mother’s side from Italy,…

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