The Nobel Prize in Physiology or Medicine 2004   Species differences The area of the olfactory epithelium (red) in dogs is some forty times larger than in humans. Mice – the species Axel and Buck studied – have about one thousand different odorant receptor types. Humans have a smaller number than mice; some of the…

The Nobel Prize in Physiology or Medicine 2004   A large family of odorant receptors Richard Axel and Linda Buck published their fundamental paper in 1991, in which they described the genes coding for a large family of odorant receptors. The odorant receptors are located on the olfactory receptor cells in the nasal cavity. Each…

New York City is my world. I was born in Brooklyn, the first child of immigrant parents whose education was disrupted by the Nazi invasion of Poland. Although not themselves learned, my parents shared a deep respect for learning. I grew up in a home rich in warmth, but empty of books, art or music.…

I was born in 1947 in Seattle, Washington, a city surrounded by mountains, forests, and the sea. My mother was the daughter of Swedish immigrants who had come to the US in the late nineteenth century while my father’s family had Irish roots on one side and ancestors extending back to the American Revolution on…

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Swedish Presentationstal av professor Sten Grillner, , i Stockholms Konserthus 10 december 2004. Professor Sten Grillner presenterar Nobelpriset i fysiologi eller medicin 2004 i Stockholms Konserthus. Eders Majestäter, Eders kungliga högheter, Mina damer och herrar, Vi uppfattar världen genom våra sinnen, vi ser färgprakten runt oss, vi lyssnar till vår omgivning, men vi…

Credits Production TWI: Narrator: Josette Simon Titles and Graphics: Kevin Cooney Editor: Gidon Benari Sound: Stuart Browne Researcher: Alex Gervin Production Manager: Kate Best Executive Producer: Rick Thomas Producer: Linda Daniel Camera: Sveriges Television AB – SVT Copyright Acknowledgements: Cell Press, an imprint of Elsevier Linda Buck Copyright © Nobel Media AB/TWI 2004

The Nobel Prize in Physiology or Medicine 2004 Credits and References for the 2004 Nobel Poster for Physiology or Medicine Scientific Advisers, Professors at Karolinska Institutet: Bertil Fredholm, Pharmacology Sten Grillner, Neurophysiology Göran K. Hansson, Medicine, Chair of the Nobel Committee Hans Jörnvall – Physiological Chemistry, Secretary of the Nobel Assembly Urban Lendahl, Genetics Illustrations…

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English Presentation Speech by Professor Sten Grillner of the , December 10, 2004. Professor Sten Grillner delivering the Presentation Speech for the 2004 Nobel Prize in Physiology or Medicine at the Stockholm Concert Hall. Your Majesties, Your Royal Highnesses, Ladies and Gentlemen, We perceive the world through our senses – we enjoy the…