I was born in 1947 in Seattle, Washington, a city surrounded by mountains, forests, and the sea. My mother was the daughter of Swedish immigrants who had come to the US in the late nineteenth century while my father’s family had Irish roots on one side and ancestors extending back to the American Revolution on…

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English Presentation Speech by Professor Lars Thelander of , December 10, 2004. Professor Lars Thelander delivering the Presentation Speech for the 2004 Nobel Prize in Chemistry at the Stockholm Concert Hall. Your Majesties, Your Royal Highnesses, Ladies and Gentlemen, This year’s Laureates in Chemistry are being rewarded for their discovery of life’s own…

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The Laureates Aaron Ciechanover, Technion (Israel Institute of Technology) Avram Hershko, Technion (Israel Institute of Technology)   Original Papers Ciechanover, A., Hod, Y., and Hershko, A. (1978) “A heat-stable polypeptide component of an ATP-dependent proteolytic system from reticulocytes”. Biochem. Biophys. Res. Commun. 81, pp. 1100-1105. Hershko, A., Ciechanover, A., and Rose, I.A. (1979) “Resolution of…

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English 6 October 2004 has decided to award the Nobel Prize in Chemistry for 2004 “for the discovery of ubiquitin-mediated protein degradation” jointly to Aaron Ciechanover Technion – Israel Institute of Technology, Haifa, Israel, Avram Hershko Technion – Israel Institute of Technology, Haifa, Israel and Irwin Rose University of California, Irvine, USA Proteins labelled for…

Swedish Presentationstal av Professor Lars Thelander, ledamot av , i Stockholms Konserthus 10 december 2004. Professor Lars Thelander presenterar Nobelpriset i kemi 2004 i Stockholms Konserthus. Eders Majestäter, Eders Kungliga Högheter, mina damer och herrar, Årets Nobelpristagare i kemi belönas för sin upptäckt av livets egen dödsmärkning och för att samtidigt ha löst…

Swedish 6 oktober 2004 har beslutat utdela Nobelpriset i kemi år 2004 “för upptäckten av ubiquitinmedierad proteinnedbrytning” gemensamt till Aaron Ciechanover Technion – Israel Institute of Technology, Haifa, Israel, Avram Hershko Technion – Israel Institute of Technology, Haifa, Israel och Irwin Rose University of California, Irvine, USA. Dödsmärkning av proteiner Proteiner bygger upp allt levande:…

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