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In 1980 Blobel proposed that newly made proteins are targeted to and imported into the various organelles within the cell by built-in signal sequences. The signals are short stretches of amino acids encoded by the gene specifying the protein. They can be located at either end of the protein, or somewhere internally.

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Christiaan Eijkman was born on August 11, 1858, at Nijkerk in Gelderland (The Netherlands), the seventh child of Christiaan Eijkman, the headmaster of a local school, and Johanna Alida Pool. A year later, in 1859, the Eijkman family moved to Zaandam, where his father was appointed head of a newly founded school for advanced elementary…

Carl Peter Henrik Dam was born in Copenhagen on 21st February 1895, to Emil Dam, apothecary, and his wife Emilie (née Peterson), a teacher. The young man graduated in chemistry from the Polytechnic Institute, Copenhagen in 1920, and the same year was appointed instructor (assistant) in chemistry at the School of Agriculture and Veterinary Medicine,…

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Presentation Speech by Professor the Count K.A.H. Mörner, Rector of the on December 10, 1902 Your Majesty, Your Royal Highnesses, Ladies and Gentlemen. Among the stipulations Alfred Nobel set forth in his will, on which the Nobel Foundation is based, that concerning the international character of the prizes occupies an important place. This proves not…

In regard to Dam’s and Doisy’s works, Professor A. Lichtenstein, Member of the Staff of Professors of the , made the following statement The Nobel Prize for Physiology or Medicine has been awarded this year for theoretically and practically important discoveries regarding the clotting or coagulation of the blood. The Danish investigator Henrik Dam received…

Scientific Advisors, Professors at Karolinska Institutet: Bo Angelin – Clinical Metabolism Bertil Daneholt – Molecular Genetics Hans Jörnvall – Physiological Chemistry Ralf Pettersson – Molecular Biology Nils Ringertz – Medical Cell Genetics and Secretary of the Nobel Assembly Art Director: Urban Frank Computer Graphics: Deborah Strand Medical Writer: Anders Nystrand Photo: Ilpo Okkonen,Oulu, Finland (Picture…