The Laureates Aaron Ciechanover, Technion (Israel Institute of Technology) Avram Hershko, Technion (Israel Institute of Technology)   Original Papers Ciechanover, A., Hod, Y., and Hershko, A. (1978) “A heat-stable polypeptide component of an ATP-dependent proteolytic system from reticulocytes”. Biochem. Biophys. Res. Commun. 81, pp. 1100-1105. Hershko, A., Ciechanover, A., and Rose, I.A. (1979) “Resolution of…

    (press release), The Royal Swedish Academy of Sciences. Boyer, P.D., The binding change mechanism for ATP synthase – Some probabilities and possibilities, Biochimica et Biophysica Acta (1993) 1140, 215-250. Abrahams, J.P., Leslie, A.G., Lutter, R., and Walker, J.E., Structure at 2.8 Å resolution of F1-ATPase from bovine heart mitochondria, Nature (1994) 370, 621-628.…

Credits Production TWI: Narrator: Josette Simon Titles and Graphics: Kevin Cooney Editor: Gidon Benari Sound: Stuart Browne Researcher: Alex Gervin Production Manager: Kate Best Executive Producer: Rick Thomas Producer: Linda Daniel Camera: Sveriges Television AB – SVT Copyright Acknowledgements: Cell Press, an imprint of Elsevier Technion, Israel Institute of Technology Typoform for the Royal Swedish…

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Presentation Speech by Professor A. Fredga, member of the Nobel Committee for Chemistry of Your Majesty, Your Royal Highnesses, Ladies and Gentlemen. In our days, the chemistry of natural products attracts a very lively interest. New substances, more or less complicated, more or less useful, are constantly discovered and investigated. For the determination of the…

A central theme of organic chemistry is the desire to understand important biological processes through discovering and imitating the manner in which Nature constructs its key substances from their basic chemical elements. Constructing artificial versions of natural products from its chemical building blocks traditionally involved a large degree of trial and error, and consequently the…

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Swedish Presentationstal av Professor Lars Thelander, ledamot av , i Stockholms Konserthus 10 december 2004. Professor Lars Thelander presenterar Nobelpriset i kemi 2004 i Stockholms Konserthus. Eders Majestäter, Eders Kungliga Högheter, mina damer och herrar, Årets Nobelpristagare i kemi belönas för sin upptäckt av livets egen dödsmärkning och för att samtidigt ha löst…

Contents: Based on materials from the 1997 Nobel Poster for Chemistry.