Nobel Prize

Selman Abraham Waksman was born in Priluka, near Kiev, Russia, on July 22nd, 1888, as the son of Jacob Waksman and Fradia London. He received his early education primarily from private tutors, and completed his school training in Odessa in an evening school and with private tutors. He obtained his matriculation diploma in 1910 from…

Ragnar Arthur Granit was born in the parish of Helsinge, Finland, on October 30th, 1900, eldest son of the Crown forester Arthur Wilhelm Granit and his wife Albertina Helena Malmberg. The family then moved to the neighbourhood of Helsingfors where his father opened a firm dealing with sylviculture and forest produce and the son became…

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Presentation Speech by Professor W. Wernstedt, Dean of the , December 10, 1927 Your Majesty, Your Royal Highnesses, Ladies and Gentlemen. Few diseases have the power of inspiring fear to the same degree as cancer. However, who would be surprised at that? How many times is this affliction not synonymous with a long, painful and…

KAROLINSKA INSTITUTET October 1977 has decided that the Nobel Prize in Physiology or Medicine for 1977 should be divided, one half being awarded jointly to Roger Guillemin and Andrew Schally for their discoveries concerning “the peptide hormone production of the brain” and the other half to Rosalyn Yalow for “the development of radioimmunoassays of peptid…

  Presentation Speech by Professor Börje Cronholm of the Karolinska Medico-Chirurgical Institute Translation from the Swedish text Your Majesty, Your Royal Highnesses, Ladies and Gentlemen, Animal behavior has fascinated man since time immemorial as can be witnessed by the important role of animals in myths, fairy-tales and fables. However, for too long man has tried…

In many inherited diseases, proteins are mislocalized in the cell due to errors in targeting signals and transport. One example is “primary hyperoxaluria,” a rare disease, which results in kidney stones already at an early age. A signal in the enzyme alanine:glyoxylate aminotransferase normally directs it to the peroxisome. In patients, this signal is altered…