4. In hereditary forms of prion diseases, a genetic change (a mutation represented by the red dot) in one of the two genes encoding PrPc, may result in a slightly altered structure of the PrPc-protein. The mutation makes it easier for PrPc to change its conformation into PrPSc, initating a chain reaction that will result…

An animation illustrating the discovery the 1997 Nobel Prize in Physiology or Medicine, shown during the press conference on October 6, 1997 at Karolinska Institutet, is presented here. The latter part of the presentation contains only images and text. This is a 2.7 Mb Shockwave animation. To download the Shockwave player, click on the icon…

8. In the 1950s and 1960s, the Nobel Laureate studied a disease called kuru which spread among the Fore people in New Guinea through cannibalistic rituals. Kuru means shivering or trembling in the Fore language. The picture, taken by Gajdusek in 1957, shows an 8-year old girl in an advanced stage of kuru.

6. This microscopic picture shows a histological section from a prion-infected brain. (1) Vacuoles that are formed as a result of neuronal cell death, results in a sponge-like appearance of the brain.  

Animations Animation: Water channels in cell membranes I Usage of these pictures and movies are subject to permission from Drs. Emad Tajkhorshid () and Klaus Schulten (). A reference to the original source is required (Tajkhorshid, E., Nollert, P., Jensen, M.O., Miercke, L.J., O’Connell, J., Stroud, R.M., and Schulten, K. (2002). Science 296, 525-530). Phone:…

The Nobel Laureate , Fritz-Haber-Institut der Max-Planck-Gesellschaft Animation , Fritz-Haber-Institut, Max-Planck-Gesellschaft Scientific review articles Imbihl, R., Ertl, G. Oscillatory Kinetics in Heterogeneous Catalysis. Chemical Review 1995(95) 697–733 Ertl, G. Primary Steps in Catalytic Synthesis of Ammonia. Journal of Vacuum Science and Technology A 1(2) 1247–1253 (1983) Ertl G. Elementary Processes at Gas/Metal Interfaces. Angewandte Chemie…

The Loker Hydrocarbon building (east elevation) Photo: Adrian Velicescu Located at the heart of the University of Southern California campus in Los Angeles, California, the Loker Institute’s 43,000 square feet building features well-equipped state-of-the art laboratories and an attractive work environment. The George and Judy Olah library and the splendid reading room atop the building…

The Laureates , Johns Hopkins University School of Medicine , The Rockefeller University Animations Original papers “Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein”. Preston, G.M., Carroll, T.P., Guggino, W.B., and Agre, P. (1992). Science 256, 385-387. “Reconstitution of functional water channels in liposomes containing purified red cell CHIP28 protein”. Zeidel,…

  Martin Chalfie at a press conference at University of Columbia, 8 October 2008. Copyright © University of Columbia 2008 Photo: Eileen Barroso Martin Chalfie at a press conference at University of Columbia, 8 October 2008. Copyright © University of Columbia 2008 Photo: Eileen Barroso Eric Kandel (left), Nobel Laureate in Physiology or Medicine 2000,…

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