1945 Medicine Laureate Sir. Alexander Fleming was awarded the prize because of his discovery of penicillin

© Nobel Media. Photo: Alexander Mahmoud

Facts on the Nobel Prize in Physiology or Medicine

On 27 November 1895, Alfred Nobel signed his last will and testament, giving the largest share of his fortune to a series of prizes, the Nobel Prizes. As described in Nobel’s will, one part was dedicated to “the person who shall have made the most important discovery within the domain of physiology or medicine”. Learn more about the Nobel Prize in Physiology or Medicine from 1901 to 2024.

Number of Nobel Prizes in Physiology or Medicine

115 Nobel Prizes in Physiology or Medicine have been awarded since 1901. It was not awarded on nine occasions: in 1915, 1916, 1917, 1918, 1921, 1925, 1940, 1941 and 1942.

Why were the medicine prizes not awarded in those years? In the statutes of the Nobel Foundation it says: “If none of the works under consideration is found to be of the importance indicated in the first paragraph, the prize money shall be reserved until the following year. If, even then, the prize cannot be awarded, the amount shall be added to the Foundation’s restricted funds.” During World War I and II, fewer Nobel Prizes were awarded.

Shared and unshared Nobel Prizes in Physiology or Medicine

40 medicine prizes have been given to one laureate* only.
36 medicine prizes have been shared by two laureates.
39 medicine prizes have been shared between three laureates.

Why is that? In the statutes of the Nobel Foundation it says: A prize amount may be equally divided between two works, each of which is considered to merit a prize. If a work that is being rewarded has been produced by two or three persons, the prize shall be awarded to them jointly. In no case may a prize amount be divided between more than three persons.

Number of Nobel Prize laureates in physiology or medicine

229 individuals have been awarded 1901-2024.

List of all Nobel Prize laureates in physiology or medicinene

Youngest medicine laureate

The Nobel Prize in Physiology or Medicine 1923

“for the discovery of insulin”

Oldest medicine laureate

The Nobel Prize in Physiology or Medicine 1966

“for his discovery of tumour-inducing viruses”

Female Nobel Prize laureates in physiology or medicine

Of the 229 individuals awarded the Nobel Prize in Physiology or Medicine, 13 are women. Of these 13, Barabara McClintock is the only one who has received an unshared Nobel Prize.

The Nobel Prize in Physiology or Medicine 1947

“for their discovery of the course of the catalytic conversion of glycogen”

The Nobel Prize in Physiology or Medicine 1977

“for the development of radioimmunoassays of peptide hormones”

The Nobel Prize in Physiology or Medicine 1983

“for her discovery of mobile genetic elements”

The Nobel Prize in Physiology or Medicine 1986

“for their discoveries of growth factors”

The Nobel Prize in Physiology or Medicine 1988

“for their discoveries of important principles for drug treatment”

The Nobel Prize in Physiology or Medicine 1995

“for their discoveries concerning the genetic control of early embryonic development”

The Nobel Prize in Physiology or Medicine 2004

“for their discoveries of odorant receptors and the organization of the olfactory system”

The Nobel Prize in Physiology or Medicine 2008

“for their discovery of human immunodeficiency virus”

The Nobel Prize in Physiology or Medicine 2009

“for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase”
“for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase”

The Nobel Prize in Physiology or Medicine 2014

“for their discoveries of cells that constitute a positioning system in the brain”

The Nobel Prize in Physiology or Medicine 2015

“for her discoveries concerning a novel therapy against Malaria”

The Nobel Prize in Physiology or Medicine 2023

“for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19”

List of all female Nobel Prize laureates

Multiple Nobel Prize laureates in physiology or medicine

No one has been awarded the Nobel Prize in Physiology or Medicine more than once. Yet …

List of multiple Nobel Prize laureates within other prize categories

Posthumous Nobel Prizes in Physiology or Medicine

There have been no posthumous Nobel Prizes in Chemistry. From 1974, the Statutes of the Nobel Foundation stipulate that a Nobel Prize cannot be awarded posthumously, unless death has occurred after the announcement of the Nobel Prize. Before 1974, the Nobel Prize has only been awarded posthumously twice: to Dag Hammarskjöld (Nobel Peace Prize 1961) and Erik Axel Karlfeldt (Nobel Prize in Literature 1931).

Following the 2011 announcement of the Nobel Prize in Physiology or Medicine, it was discovered that one of the medicine laureates, Ralph Steinman, had passed away three days earlier. The Board of the Nobel Foundation examined the statutes, and an interpretation of the purpose of the rule above lead to the conclusion that Ralph Steinman should to remain a Nobel Prize laureate, as the Nobel Assembly at Karolinska Institutet had announced the 2011 Nobel Prize laureates in physiology or medicine without knowing of his death.

Family Nobel Prize laureates in physiology or medicine

Forced to decline the Nobel Prize

Two Nobel Prize laureates in chemistry have been forced by authorities to decline the Nobel Prize. Adolf Hitler forbade three German Nobel Prize laureates from receiving the Nobel Prize – two of whom were awarded the Nobel Prize in Chemistry, Richard Kuhn in 1938 and Adolf Butenandt in 1939. The third person, Gerhard Domagk was awarded the Nobel Prize in Physiology or Medicine in 1939. All of them could receive the Nobel Prize diploma and medal later, but not the prize amount.

Nobel Prize laureate partnerships in biomedical science

Many long scientific partnerships have resulted in Nobel Prizes:

Partners Years of
Partnership
Dates
Michael S. Brown & Joseph L. Goldstein 40 1972-present
Carl Cori & Gerty Cori 34 1922-56
William H. Stein & Stanford Moore 33 1939-72
André F. Cournand & Dickinson W. Richards 30 1932-62
George H. Hitchings & Gertrude B. Elion 23 1944-67
David H. Hubel & Torsten N. Wiesel 20 1958-78
J. Michael Bishop & Harold E. Varmus 19 1971-90
Philip S. Hench & Edward C. Kendall 16 1934-50
Edmond H. Fischer & Edwin G. Krebs 11 1953-64
François Jacob & Jacques Monod 9 1957-66
James Watson & Francis Crick 2 1951-53

List compiled in 2012, courtesy of Joseph L. Goldstein.

Nominations for the Nobel Prize in Physiology or Medicine

In the nomination database, you can find interesting nomination trivia, for example, that the Austrian neurologist and founder of psychoanalysis Sigmund Freud (1856-1939) was nominated 32 times for the Nobel Prize in Physiology or Medicine, but never awarded. In 1929, the Nobel Committee for Medicine engaged an expert who concluded that a further investigation in Freud was not necessary, since Freud’s work was of no proven scientific value. Freud was also nominated once for the 1936 Nobel Prize in Literature by Nobel Prize laureate Romain Rolland, an acquaintance of Freud.

The nominations for the Nobel Prizes are kept secret for 50 years.

Explore the nomination database for the Nobel Prizes

The Nobel Prize medal in physiology and medicine

The Nobel Prize medal in physiology and medicine was designed by Swedish sculptor and engraver Erik Lindberg and represents the Genius of Medicine holding an open book in her lap, collecting the water pouring out from a rock in order to quench a sick girl’s thirst.

Read more about Nobel medal in Physiology and Medicine

The Nobel Prize diplomas

Each Nobel Prize diploma is a unique work of art, created by foremost Swedish and Norwegian artists and calligraphers.

More about the Nobel Prize diplomas

The Nobel Prize amount

Alfred Nobel left most of his estate, more than SEK 31 million (today approximately SEK 2,2 billion) to be converted into a fund and invested in “safe securities.” The income from the investments was to be “distributed annually in the form of prizes to those who during the preceding year have conferred the greatest benefit to humankind.”

The Nobel Prize amount for 2024 is set at Swedish kronor (SEK) 11.0 million per full Nobel Prize.

More about the Nobel Prize amount


*Why “laureate”?

Why are the individuals and organisations awarded a Nobel Prize called Nobel Prize laureate? The word “laureate” refers to being signified by the laurel wreath. In Greek mythology, the god Apollo is represented wearing a laurel wreath on his head. A laurel wreath is a circular Crown made of branches and leaves of the bay laurel (in Latin: Laurus nobilis). In Ancient Greece, laurel wreaths were awarded to victors as a sign of honour – both in athletic competitions and in poetic meets.


More facts on the Nobel Prizes

First published 5 October 2009.

To cite this section
MLA style: Facts on the Nobel Prize in Physiology or Medicine. NobelPrize.org. Nobel Prize Outreach AB 2024. Sun. 24 Nov 2024. <https://www.nobelprize.org/prizes/facts/facts-on-the-nobel-prize-in-physiology-or-medicine>